(001507) Nophalac Solution 670mg/ml x 100ml
Indications / Uses
Constipation: Regulation of the physiological rhythm of the colon.
Portal systemic encephalopathy (PSE): Treatment and prevention of hepatic coma or precoma.
Where a soft stool is considered of medical benefit (haemorrhoids, after colon/anal surgery).
Dosage / Direction for Use
Dosing in constipation or where soft stool is considered of medical benefit: Adults: Starting dose: 15-45 ml. Maintenance dose: 15-30 ml.
Children (7-14 years): Starting dose: 15 ml. Maintenance dose: 10-15 ml.
Children (1-6 years): Starting dose: 5-10 ml. Maintenance dose: 5-10 ml.
Infant under 1 year: Starting dose: 5 ml. Maintenance dose: 5 ml.
Dosing in precoma and coma hepaticum (for adults only): Starting dose: 30-45 ml, three to four times daily.
The maintenance dose should be adjusted so that soft stools are produced 2-3 times daily.
The starting dose can be adjusted to the individual after reaching adequate treatment effect (maintenance dose). Several days (2-3 days) of treatment may be needed in some patients before treatment effect occurs.
During the therapy with laxatives it is recommended to drink sufficient amounts of fluids (1.5–2 litres, equal to 6-8 glasses) during the day.
Administration: Lactulose can be taken as a single daily dose or in two divided doses. Dose need to be taken in one swallow. It should not be held in the mouth for length of time.
Dosage will be adjusted to individual needs. NOPHALAC is best taken at the same time each day, preferably at breakfast time.
Nophalac can be taken diluted or undiluted.
Patients who are intolerant to lactose should take NOPHALAC oral solution with care. The dose normally used in constipation should not pose a problem for diabetics. The dose used in the treatment of (pre) coma hepaticum is usually much higher and should be taken into consideration for diabetics. Laxatives (of any kind) should be used when absolutely necessary and only after consulting a doctor. Faecal retention abilities could be disturbed during treatment with NOPHALAC oral solution.
Patience with the rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. It should be taken into consideration that the exoneration reflex could be disturbed during the treatment. In case of insufficient therapeutic effect after several days, consultation of a physician is advised.